Paul Offit Exposes the Florida Surgeon General’s Anti-Vax Warning

Infectious Disease
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COVID-19 Vaccine
by
Emily Hutto, Associate Video Producer
January 5, 2024
Florida Surgeon General Joseph Ladapo, MD, PhD, recently issued a statement that COVID-19 mRNA vaccines should not be used. In this video interview, Paul Offit, MD, of Children’s Hospital of Philadelphia, discusses Ladapo’s statement and how the vaccines are made.
The following is a transcript of his remarks:
On January 3 of 2024, the surgeon general of Florida, Dr. Joseph Ladapo, put out a warning that physicians and healthcare providers in this state, Florida, should not use mRNA vaccines. The reason is that supposedly they were contaminated with DNA fragments that would then insert themselves into human DNA and could cause cancers like leukemia or lymphoma or autoimmune diseases or other problems.
So is that possible? Is it possible that Dr. Ladapo is correct and that for that reason we should avoid mRNA-containing vaccines? In order to understand the answer to that question, you need to understand how mRNA vaccines are made. So, we’ll start at the beginning.
What you start with when you make an mRNA vaccine is a small circular plasmid of DNA, double-stranded DNA, into which is inserted the gene that codes for the SARS-CoV-2 spike protein. You then amplify that plasmid in bacteria — you cut the bacteria, you’ve released the plasmid, then you cut out that small piece of DNA. Then you use an enzyme, RNA polymerase, to transform that DNA into messenger RNA. There are a variety of purification steps, there are filtration steps, there’s treatment with DNA ACE1, which is an enzyme that cuts DNA.
So is it possible that despite purification and filtration that you are left with small amounts of fragmented DNA? Yes, you are. You have roughly a billionth of a gram, nanograms, of this fragmented DNA.
So could that DNA then affect your DNA? In order for that to happen, three things would have to occur, all of which are for the most part impossible.
The first is that the DNA would have to enter your cytoplasm. Now, our cytoplasm hates foreign DNA and it has a variety of mechanisms, including innate immunological mechanisms and enzymes, to destroy foreign DNA.
Then that DNA, which would never survive the cytoplasm, would have to then cross the nuclear membrane into the nucleus, which would require a nuclear access signal that these DNA fragments don’t have.
Even if they entered the nucleus, which they can’t, they would have to insert themselves into your DNA, which means they would have to cut your DNA, which would require enzymes like integrases, which they also don’t have.
So the chance that DNA could affect your DNA is zero.
It’s interesting that the minute you bring up the notion of foreign DNA,
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