Amy Schumer recently shared that she has been diagnosed with Cushing syndrome, a condition caused by an excess of cortisol in the body. This revelation followed comments from fans about her face appearing puffier than usual.
During an interview with Jessica Yellin for the News Not Noise newsletter, Schumer expressed her relief at the diagnosis. She explained the different types of Cushing syndrome, some of which can have severe consequences like requiring brain surgery or adrenal gland removal. Despite undergoing extensive medical testing during press for her show, Life & Beth, Schumer mentioned feeling grateful that the type of Cushing she has will resolve on its own.
According to the Mayo Clinic, Cushing syndrome occurs when the body has an elevated level of cortisol over a prolonged period. Symptoms can include various types of weight gain, including facial puffiness. Initially, discussions about Schumer’s appearance on the internet caused stress, but it ultimately led her to seek a diagnosis.
Schumer humorously recalled how internet comments also prompted her to rename her son, Gene David, after realizing that his original name, Gene Attell, sounded like a less than flattering combination. She acknowledged the power of the internet in both raising awareness about her health and influencing her decisions.
In response to concerns about her appearance and health issues, Schumer mentioned having endometriosis and highlighted the understudied nature of women’s bodies. She encouraged her followers to educate themselves about these issues by reading “All In Her Head” by Elizabeth Comen.
In conclusion, Schumer’s journey with Cushing syndrome sheds light on the importance of self-awareness, seeking medical help, and advocating for better understanding of women’s health issues. Her story serves as a reminder that listening to our bodies and addressing concerns promptly is crucial for overall well-being.

