When we hear the word “twins”, we tend to think of two identical people who share physical traits, and perhaps certain behaviours or quirks. However, in the world of technology this word has a different meaning. It refers to something both revolutionary and still relatively underexplored: digital twins.
A digital twin is a virtual replica of a real system, a dynamic model that, fed by real-time data, mimics the behaviour of what it represents. It is like having a smart mirror that not only reflects something’s state, but also learns from each movement it makes in order to predict the next.
Digital twins have been used in various sectors for years. They help us to predict aircraft faults before they occur, to optimise entire factories, and to design cars that learn from thousands of users’ driving data. More recently, this technology is being applied in agriculture, leading to significant advances in, for instance, predicting the impacts of climatic and natural changes on crops.
In medicine, digital twins are a gamechanger. There are, for instance, approaches based on cardiac digital twins that simulate the functioning of each patient’s heart with a remarkable level of detail. This will allow doctors to anticipate how a specific heart will respond to an arrhythmia or a specific treatment, all without ever putting the actual patient at risk.
This combination of virtual modelling and clinical data opens the door to more predictive, personalised and safer medicine, where therapeutic decisions are based not only on medical experience, but also on simulations of what will happen in a patient’s digital twin. But what happens if we apply this to the human brain?
From factories to brains
Cognitive and mental health are pillars of human well-being, but they are also fragile. Age-related decline, depression, anxiety and neurodegenerative disorders still present major challenges for medicine.
This is where artificial intelligence (AI) offers a window of hope. By integrating and analysing large volumes of data, AI can help detect disease earlier, better select patients for clinical trials, and even simulate each individual’s progression using digital twins. AI offers a way to stay ahead of deterioration, design tailor-made interventions, and speed up the development of safer, more effective therapies.
A team of scientists from Duke University, Columbia University, Nebrija University, and CogniFit have recently developed a new framework for addressing people’s mental and cognitive health through digital cognitive twins. These are virtual representations that integrate data from our brain and behavioural activity, our daily habits, and our emotional responses. By using AI, these dynamic models can learn and update themselves with each new interaction.
We envisage that every person could have their own cognitive “digital twin”, which can be used to predict how their memory or attention span will evolve, and to suggest personalised activities to train the mind before a serious problem arises.
Read more:
What are digital twins? A pair of computer modeling experts explain
Adapting existing tech
The key to this revolution lies in integrating the devices many of us already have – things like smart watches,

